REQ-10059603
8月 08, 2025
Ireland

摘要

The Risk-Based Quality Management (RBQM) Risk surveillance Lead is responsible driving the adoption of RBQM practice at trial level and oversee the implementation, and continuous improvement. Risk Surveillance Lead works within a matrix environment and has overall account-ability for the surveillance of the quality risks across the assigned trials and program, enabling a comprehensive clinical quality (GCP) risk governance. The role demonstrates leadership in influencing and improving clinical trial quality through the expert understanding of clinical trial protocols, processes, regulatory requirements, and quality management principles.


This role can be based in our offices in Dublin, Ireland or Barcelona, Spain. On site expectation of three days in the office.

#LI-hybrid

About the Role

Major Accountabilities:

  • Facilitate trial protocol risk assessment across multiple cross-functional domains (clinical, operational, data management, vendors, regulatory etc.) associated to critical-to-quality (CtQ) data and processes, including definition of quality tolerance limits (QTLs), evaluation of risks based on likelihood, detectability, impact, and ensures mitigation strategy / plans are defined
  • Responsible for drafting, maintaining, and archiving the study specific documentation of risk management activities e.g., Integrated Quality Risk Management Plan (IQRMP)
  • Partners with the RBQM system configuration team to ensure risk indicators, quality tolerance limits and other analytics/visualizations are programmed and functioning per operational requirements in the RBQM system
  • Conduct of periodic central surveillance of the aggregate data at the study and potentially program level, leveraging available analytics/visualizations in the RBQM system, to identify emerging risks and/or issues
  • Facilitate risk review meetings and discussions with study and potentially program team members to effectively communicate and discuss the findings, support, and encourage robust root cause identification and mitigation strategies
  • Supports and participates in internal and external audits and inspection
  • Collaborate with training departments to support training initiatives and aid in the adoption of the RBQM approach.
  • Identifies and shares lessons learned, best practices, successes, case studies, failures, and process improvement opportunities to promote continuous improvement and consistency with RBQM processes
  • Acts as a change agent, champion, subject matter expert and point of contact of RBQM methodology, leading study teams to understand and follow the best practices to achieve maximum benefit
Experience:

Bachelor’s Degree in a health-related, life science area, or equivalent combination of education, training, and work experience

  • Minimum of 4 years of experience in the pharmaceutical or CRO industry
  • Preferred minimum of 1 years of experience in Risk Based Quality Management
  • Robust understanding of the drug development process and clinical trial execution
  • Knowledge of industry regulatory standards including 21 CFR Part 11, ICH E6, ICH E8 (GCP)
  • Experience in risk management, sponsor audits and health authority inspections, root cause analyses and mitigation strategies as well as Corrective Actions Preventive Actions
  • Knowledge of RBQM IT systems or other data analytic systems
  • Demonstrated ability to analyze data, identify patterns and make recommendations for improvement
  • Demonstrated ability to effectively lead cross functional team meetings
  • Experience forming cross-functional collaborations; strong interpersonal skills
  • Supports a culture of continual improvement and innovation; promotes knowledge sharing
  • Ability to influence without authority
  • Thinks creatively; challenges the status quo

Languages:

English: fluent written and spoken

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Development
Innovative Medicines
Ireland
Dublin (NOCC)
Barcelona Gran Vía, Spain
London (The Westworks), United Kingdom
Research & Development
Full time
Regular
No

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REQ-10059603

Risk Surveillance Lead

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