Senior Expert Science & Technology - PRD Chemist

Your Responsibilities:

• With your strong expertise and creativity in chemical synthesis and process development, you take a leading role in setting up future chemistry and manufacturing pathway for Antibody-Oligonucleotide-Conjugates (AOCs) and other complex constructs.
• You will be a key contributor to engage and ensure adequate support and knowledge transfer for Novartis BD&L activities focussing on bioconjugation chemistry and manufacturing processes.
• In our labs, your experimental designs will be executed and allow you to interpret and report data and results
• Further, he/she coordinates and ensures timely availability and transfer of manufacturing instructions to pilot plant within Chemical & Analytical Development (CHAD) or CMOs.
• As a core member of cross-functional teams, you collaborate closely with our internal and external partners to ensure timely and quality delivery of new nucleotide drugs to our patients
• Further, you will provide relevant process documentation in support of filing of dossiers.
• You will also actively participate in scientific exchange groups within Novartis and Academia and maintain excellent collaboration with our customers.

Minimum Requirements:

Education:

We are looking for candidates with PhD and PostDoc in organic chemistry preferably with specialization in the field of bio-conjugation or chemical modification of fermentation products.

Experience and Expertise:

In addition, the ideal candidate would have the following professional experience:

• Recent and proven knowledge in space of chemical bioconjugation or chemical modification of fermentation products, e.g. Antibody-Drug Conjugations, etc. or other complex molecular structures is an essential requirement
• 2-5 years experience in synthesis/ chemical process development is a strong requirement, experience in piloting experience under GMP is a benefit
• Independent and self-motivated workstyle with team orientation and adequate communication style is an essential requirement
• Advanced knowledge of software and computer tools such as Office package, DoE tools, etc. is desirable

Language Skills:

• Adequate knowledge of English language is a requirement (oral and written), German and other language skills are beneficial.

Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Accessibility and accommodation
Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to [email protected] and let us know the nature of your request and your contact information. Please include the job requisition number in your message.