Director, Toxicology Multiple Therapeutic Areas

Key Responsibilities:

• ​​Leads PCS Target Teams to design, integrate and interpret results of nonclinical safety assessment program including impact to drug development and/or project timeline 
• Represents PCS on cross functional R&D project teams to design appropriately compliant and scientifically relevant nonclinical safety package 
• Recognize the need for a “fit for purpose and modality” nonclinical program as needed and collaborate with line functions outside of PCS to accomplish this goal 
• Participates in internal Novartis initiatives to improve use of nonclinical/translational safety data for drug development decisions. 
• Manages communications and builds relationships between PCS and R&D project teams 
• Negotiates with Global Health Authorities (HA) worldwide regarding safety issues, scientific interpretation and acceptability nonclinical safety package to support clinical trials and market approval. 
• Responsible for authoring nonclinical safety sections of internal and regulatory documents supporting clinical development and market approval 
• May evaluate in/out-licensing opportunities and carries out technical Due Diligence activities upon request. 
• Participates or leads internal and/or external cross-functional groups on key initiatives focused on PCS objectives and/or current nonclinical safety topics. 
• Mentors colleagues on drug development strategy and project-related matters  

Essential Requirements: 

•  Minimum of 5 years experience as a nonclinical safety Project Team member; Demonstrated experience in the preclinical development of small molecule, oligonucleotides and/or biotherapeutics and the safety issue awareness of these modalities. 
• 8+ years experience in a nonclinical drug development scientific discipline (e.g. study director, project team toxicologist or pharmacologist). 
• Demonstrated experience in direct or written communication of strategy and data to global health authorities, supporting clinical development and market approval. 
• Knowledge of drug development strategy for immunomodulatory drugs 
• Leadership in cross-industry organizations (discipline-related or related to drug development). 
• Excellent interpersonal, leadership, organizational skills (e.g. planning and time management) and teamwork skills. Excellent oral and written communication and influencing skills. Highly efficient, self-motivated, flexible and able to work independently and efficiently under time constraints. 
• Ability to focus and work on several projects simultaneously and to effectively manage conflicting expectations from the line unit, TA Strategy team and project teams in a matrix management environment. 
• Customer focused thinking. Recognized ability to represent PCS on Novartis cross functional decision boards or other cross functional project teams. 
• Recognized expertise in technical and scientific problem solving in a project driven, multi-disciplinary international environment. 
• Ability to mentor and coach   

The salary for this position is expected to range between $185,500 and $344,500 per year.

The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors. Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards. US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.

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